IndraLab

Statements


VCP activates VCPIP1. 3 / 3
| 3

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"We observe competition between VCPIP1 and other cofactors for VCP binding and show that VCP stimulates VCPIP1's DUB activity."

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"Skillfully reversing ubiquitination, the deubiquitinase VCIP135 mediated by VCP/NSFL1C takes charge of orchestrating a seamless remodeling of the Golgi membrane (36, 39)."

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"We find that VCP stimulates VCPIP1's DUB activity and use mutagenesis and single-molecule mass photometry assays to test the structural model."