IndraLab

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Desflurane activates KCNK18. 3 / 3
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"In the Xenopus oocyte and COS-7 cell expression systems, clinical doses of isoflurane, halothane, sevoflurane, and desflurane strongly increase TRESK currents up to three-fold by increasing the open probability [XREF_BIBR]."
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"Human TRESK is potently activated by halothane, isoflurane, sevoflurane, and desflurane, making it the most sensitive volatile anesthetic activated K2P channel yet described."
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"Human TRESK is potently activated by halothane, isoflurane, sevoflurane, and desflurane, making it the most sensitive volatile anesthetic-activated K2P channel yet described."
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