IndraLab

Statements

Modified USP15 leads to the ubiquitination of MDM2. 2 / 2

| 2

reach

"Loss of USP15 in melanoma and colorectal cell lines caused spontaneous ubiquitination and degradation of MDM2, suggesting that the amount of MDM2 in cancer cells is maintained by a dynamic balance between ubiquitination and deubiquitination."

24777531

➶

reach

"In colorectal cell lines, loss of USP15 caused ubiquitination and degradation of MDM2, which indicated that the amount of MDM2 is maintained by the dynamic balance between ubiquitination and deubiquitination XREF_BIBR."

33061808

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Modified USP15 leads to the ubiquitination of MDM2. 2 / 2

INDRA sources:

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