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P5091 activates WNT1. 1 / 1

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"It demonstrated that in Usp7 RNAi worms, the tail-less regeneration phenotype was regulated by the Islet/Wnt1 axis.In addition, it was reported that USP7 is a tumor-specific Wnt activator that mediates the treatment of APC-mutated colorectal cancer [38], and the USP7 inhibitor P5091 attenuated wnt1 activity in the Wnt signaling pathway and inhibited the growth of colorectal cancer [39]."

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P5091 activates WNT1. 1 / 1

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