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Statements


TNF inhibits USP2. 2 / 2
| 2

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"TNF-α treatment downregulated USP2 (Fig. 5D and F)."

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"However, tumour necrosis factor alpha (TNFalpha) has been reported to downregulate a USP2 isoform in hepatocytes 8, so possibly, USP2 inhibited degradation of LDLR is a pathway that is affected in inflammatory conditions."