IndraLab

Statements


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"Indeed, we were able to detect a constitutive interaction between endogenous USP15 and BRAP in (both stimulated and unstimulated) HEK293T cells (XREF_FIG B)."

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"This reinforces the notion that although both USP4 and USP15 can interact with BRAP under certain experimental conditions, the USP15 : BRAP rather than USP4 : BRAP interaction may be of most relevance within a physiological setting."

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"In this study we show that CRAF expression levels are controlled by the BRAP binding partner USP15, which therefore acts as a positive regulator of MAPK signaling."