IndraLab

Statements

USP18 activates isopeptidase. 3 / 3
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reach
"USP18 can increase HBV susceptibility by removing isopeptidase activity of ISG15 and promoting HBV replication by downregulating the I-IFN signal transduction pathway."
28709980
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"This was accompanied by increased levels of ISGylation, suggesting a possible involvement of USP18 mediated isopeptidase activity in this process [21]."
18817868
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"This isopeptidase independent activity is mediated by the binding of USP18 to the intracellular domain of IFNAR2, which prevents the binding of JAK1."
24555472