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P5091 activates Wnt. 2 / 2

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"One of the USP7 inhibitors, P5091 represses the Wnt signaling pathway by enhancing ubiquitin mediated degradation of beta-catenin in CRC cells as well as in in vivo models [XREF_BIBR]."

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"The USP7 inhibitor P5091 has been demonstrated to effectively inhibit Wnt signaling and tumor growth, underscoring the pivotal role of USP7 in this context [28]."

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IndraLab

Statements

P5091 activates Wnt. 2 / 2

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