IndraLab

Statements

UCHL1 activates doxorubicin. 5 / 5
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"The Deubiquitinating Enzyme UCHL1 Induces Resistance to Doxorubicin in HER2+ Breast Cancer by Promoting Free Fatty Acid Synthesis."
33718207
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"Erratum : The Deubiquitinating Enzyme UCHL1 Induces Resistance to Doxorubicin in HER2+ Breast Cancer by Promoting Free Fatty Acid Synthesis."
33937091
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"A previous study showed that UCHL1 overexpression supported apoptosis in verapamil- and Adriamycin-treated hepatoma cell lines (BEL-7402 and SMMC-7721) [76]."
36233276
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"Similarly, in HER2+ breast cancer (BC), the deubiquitinating enzyme UCHL1 can induce resistance to doxorubicin by promoting the synthesis of free fatty acids (FFA; G. Lu et al., 2021)."
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"Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma."
29627846