IndraLab

Statements

NPPA activates HCN4. 2 / 2
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reach
"While additional electrophysiological and global gene expression studies are required to validate the physiological nature of ANP induced VCS cells, we provided evidence that ANP treatment can increase the gene expression of the important VCS markers (HCN4 and Cx40) in embryonic ventricular cells through the NPRA/cGMP/PKG signal transduction pathway."
29720615
reach
"Collectively, these results indicate that ANP and NPRA signaling can modulate the relative distribution of HCN4 or Cx40 positive cell fractions within the embryonic ventricular cell cultures."
29720615