IndraLab

Statements


RTN4R binds FN1 and ANPEP. 2 / 2
| 2

sparser
"The conformation imposed by mAbs C and E more strongly inhibits interactions of CD13 with fibronectin, NGR motifs, or substrates, and thus these mAbs are good inhibitors of the enzymatic activity."

sparser
"Further support for the hypothesis that the sites involved in cell-cell adhesion are not the same as those involved in binding to fibronectin and NGR motifs comes from the fact that binding of CD13 to fibronectin and NGR motifs is not favored, but rather slightly inhibited, after crosslinking by mAb 452."