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Mercaptopurine inhibits JUN. 2 / 2

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"Lastly, a combination of melatonin and mercaptopurine can be used to inhibit the c-jun signaling which is activated upon SARS-CoV-2 contributing to the pathogenesis of the disease as the signaling mediates the effect of several other host proteins known to interact with viral proteins."

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"As shown in Fig. 6d, mercaptopurine and melatonin may synergistically block c-Jun signaling by targeting multiple cellular targets."

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Mercaptopurine inhibits JUN. 2 / 2

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