IndraLab

Statements



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"3D polymerase (3D ) of EV71 entered the nucleus and targeted the central pre-mRNA processing factor 8 (Prp8) to block pre-mRNA splicing and mRNA synthesis ."

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"Moreover, 3Dpol, the enteroviral RNA-dependent RNA polymerase, enters the nucleus and targets the pre-mRNA processing factor 8 (Prp8) to block pre-mRNA splicing and mRNA synthesis [49]."

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"Picornavirus genome synthesis occurs in the cytoplasm, whereas 3D has a nuclear localization signal that enters the nucleus and targets the pre-mRNA processing factor 8 (Prp8) to block host pre-mRNA splicing and mRNA synthesis [39]."