IndraLab

Statements


RvD1 inhibits RELA. 3 / 3
| 3

reach
"RvD1 was also assumed to be a ligand for PPARgamma and inhibited IkappaBalpha degradation and NF-kappaB p65 nuclear translocation in an LPS induced lung injury model, which was partially reversed by the PPARgamma inhibitor GW9662."
| PMC

reach
"Recently, an increasing number of studies has demonstrated that RvD1 could inhibit p65 activation (an important subunit of NF-κB), which finally suppressed the NF-κB activation, resulting in a decreased inflammatory response (Zhao et al., 2016; Yin et al., 2017; Xu et al., 2018)."

reach
"Our study of signalling pathways revealed that RvD1 suppressed IL-1beta-induced activation of NF-kappaB and p65, p38 and MAPK and JNK (1/2)."