IndraLab
Statements
USP37 activates glycolytic process. 2 / 2
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2
reach
"However, whether USP37 influences keloid formation through regulating SALL4 deubiquitination is unknown.Here, we hypothesized and demonstrated that USP37 deubiquitinated and stabilized SALL4 to activate PI3K/AKT pathway, thereby promoting proliferation, invasion, migration, extracellular matrix (ECM) accumulation and glycolysis in keloid fibroblasts."