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"During beta-adrenergic stimulation, 3 '-5'-cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) phosphorylates KCNQ1, producing an increase in I Ks current and a shortening of the action potential."

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"The results of these experiments, summarized in XREF_FIG, indicate that KCNQ1 is phosphorylated in response to cAMP independent of co-expression of any of these beta subunits."