IndraLab

Statements


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"Further, inactivation of p53 by PFT-alpha or MT-AMO promoted cell growth, which was abrogated by the antisense to h-eag1 (XREF_FIG)."

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"The small molecule EAG1 blocker astemizole reduced EAG1 expressing cancer cell growth in vitro and in vivo."

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"Ectopic expression of EAG1 significantly rescued miR-296-3p-induced inhibition of cell growth and drug resistance."

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"Thus, cysteine oxidation of KCNH1 by ROS in cancer cells is expected to inhibit cancer cell growth."