IndraLab

Statements

IK binds USP47. 4 / 4
2 | 2
biogrid
No evidence text available
32377397
biogrid
No evidence text available
32377397
sparser
"In summary, we found that IK depletion impairs the proper splicing of ATM pre-mRNA at exons 1–2, which results in ATM deficiency followed by chromosome fragmentation and that USP47 directly binds to IK and deubiquitinates it leading to its stabilization."
32377397
sparser
"Next, to examine whether USP47 directly binds to IK, cell lysates expressing HA-IK and Flag-USP47 were used in a pull-down assay with anti-HA or -Flag antibodies."
32377397