IndraLab

Statements


USP4 increases the amount of SOX9. 4 / 4
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"Ectopic expression of USP4 in CRC cells induced SOX9, OCT4 and CD133 expression significantly."

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"Next we intend to further investigate the mechanism by which USP4 modulating SOX9 expression."

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"Conversely, silencing of USP4 dramatically reduced SOX9, OCT4 and CD133 levels in SW480 cells and HCT116 cells."

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"Silencing USP4 significantly decreased SOX9 expression, whereas this effect was evidently reversed by proteasome inhibitor MG132 (Fig. 3B)."