IndraLab

Statements

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"EBN at 1000 μg/mL increased cell proliferation 1.4‐fold.After EBN pretreatment, stronger cellular activity was observed."
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"In conclusion, CCK8 assays showed that the simulated digested EBN not only did not cause toxicity to cells but even promoted the proliferation and viability of epithelial cells to alleviate the damage of the alveolar epithelial layer during treatment.3.5 EBN regulates the expression of inflammatory factors in an in vitro model."
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"Results showed that EBN stimulated proliferation and activation of B cells."
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"Last but not least, EBN could also potentiate the proliferation of human peripheral blood monocytes (Ng et al., 1986)."
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"Evidence from research studies showed that EBN exerts immunostimulatory activity, induces cell division and proliferation, inactivates the influenza virus, and is implicated in the amelioration of osteoporosis conditions [4,5]."
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"However, in a study by Roh et al. (2011), EBN increased the gene expression of IL‐6 and vascular endothelial growth factor (VEGF) to induce the proliferation of human adipose‐derived stem cells, in contrast to our findings, which may be related to the complex physiological functions of IL‐6, such as its proliferative activity (Hunter & Jones, 2015)."
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"EBN stimulates epidermal growth and cell proliferation [13] and moisturizes the skin [14]."
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"An in vivo study done by Albishtue et al. to study the effects of EBN on female reproductive system using adult female Sprague Dawley rats showed that oral EBN treatment at 60 and 120 mg/kg per day for 9 weeks augmented proliferation of uterine cells, including luminal epithelium, glandular epithelium, and stromal cells, resulting in better uterine and reproductive functions."
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"Inhibition of KCNQ2 partially suppressed cell proliferation and 86 Rb uptake in MDA-MB453 cells but not in MCF-10A cells suggesting that KCNQ2 is responsible for at least some of the enhanced Rb flux.[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Hence, EBN could be used to enhance uterine functions and reproduction by increasing the proliferation of uterine structures such as LE, GE, and stromal cells."
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"A study on female rats found that EBN enhances fertility and embryo implantation by improving the differentiation and proliferation of uterine tissues, as evidenced by increased steroid receptor expressions [13]."
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"The amount of change in transdermal water loss displayed a tendency to increase in both groups at baseline and week 12, and the melanin index and erythema index decreased in both groups at baseline and week 12.There are studies that have documented that EBN containing EGF promotes and activates the synthesis of DNA, and thus promotes cell proliferation (Kong."
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"The results showed that EBN extract promoted the proliferation of normal keratinocytes and fibroblasts dose-dependently (Kong et al., 1987)."
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"Several previous studies have shown that EBN can promote cell proliferation in vitro."
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"In in vivo studies, EBN supplementation has been reported to accelerate the proliferation and activation of B cell antibodies (Zhao et al., 2016) and stimulate the proliferation of uterine structures (Albishtue et al., 2018)."
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"The study done by Roh et al. (2012) has reported that activation of cell proliferation by EBN occurs through mitogen-activated protein kinase (MAPK)."
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