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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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S-nitrosoglutathione activates UCHL1. 4 / 4

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"In case of cellular UCHL1 study, SH-SY5Y cells were treated with GSNO (500nM) and rotenone (1muM) for 16h."

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"To identify whether UCHL1 was S nitrosylated in vitro the purified recombinant UCHL1 (2mg/ml) was treated with GSNO (10 molar excess)."

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"UCHL1 wild type and TM were treated with different concentrations of GSNO and the reaction mixture was incubated at 37degreesC for 2h."

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"Recombinant UCHL1 (200mul, 250muM) was treated with different concentrations of GSNO for 2h and loaded onto a Superdex 200, 10/30 (GE Healthcare Life Sciences, USA) gel filtration column."

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S-nitrosoglutathione activates UCHL1. 4 / 4

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