IndraLab

Statements


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"Depletion of USP39 inhibits cell proliferation and migration and induces cell death in human pancreatic cancer cells."

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"Our research demonstrates that USP39 silencing can induce cell death, which is consistent with the reported functions of other deubiquitinase family members such as USP47 [47, 48] and USP7 [49–51] in cell survival regulation."

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"Using clonogenic analysis, we also confirmed that the RG/AA mutant failed to rescue USP39 knockdown-mediated cell death (Figure 3J)."