IndraLab

Statements


CYLD activates BCL3. 3 / 4
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"CYLD also contributes greatly by preventing the Bcl3 from being localized in the nucleus and thus controls tumor development and proliferation [11]."

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"Interestingly, coexpression of MKK7 and CYLD restored the nuclear presence of Bcl3 in melanoma tissues (XREF_SUPPLEMENTARY)."

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"Of importance, catalytically inactive CYLD overexpression allowed Bcl-3 to be located predominantly in the nucleus."