IndraLab

Statements


USP39 decreases the amount of TRIM26. 3 / 3
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"These data demonstrate that USP39 regulates TRIM26 pre-mRNA splicing and maturation, and led to decrease of TRIM26 protein level at least in part by suppressing splicing of its pre-mRNA."

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"We first examined the effect of USP39 on the levels of TRIM26 mRNA by using qRT-PCR, discovering that knockdown of USP39 increased transcript level of TRIM26."

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"Although our previous study found that knockdown of USP39 could increase the protein level of TRIM26, no further exploration was performed to the mechanism of USP39 regulating TRIM26."