IndraLab

Statements

USP22 binds ADAM9. 8 / 8
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sparser
"Understanding the USP22-ADAM9 axis offers novel insights into the molecular mechanisms underlying PE and highlights potential therapeutic targets for its prevention and treatment."
41201036
reach
"To clarify the interaction between USP22 and ADAM9, Co-IP assay was performed."
38176298
reach
"In addition, we also found USP22 bound to ADAM9 to suppress the activation of Wnt/β-catenin pathway."
38176298
sparser
"This stabilization was confirmed through co-immunoprecipitation assays, demonstrating a direct interaction between USP22 and ADAM9 ( xref )."
41201036
sparser
"To clarify the interaction between USP22 and ADAM9, Co-IP assay was performed."
38176298
sparser
"Besides that, our findings also verified that USP22 interacted with ADAM9 to mediate the activation of Wnt/β-catenin pathway in trophoblast cells."
38176298
sparser
"In addition, we also found USP22 bound to ADAM9 to suppress the activation of Wnt/β-catenin pathway."
38176298
sparser
"Additionally, the USP22-ADAM9 interaction influences the Wnt/β-catenin signaling pathway, which governs cellular proliferation, migration and EMT ( xref )."
41201036