IndraLab

Statements

Lamotrigine inhibits KCNH2. 2 / 3

1 | 2

reach

"Additionally, the potency (IC ) of lamotrigine to block the hERG potassium channel, responsible for cardiac repolarization, was reported as 229 μM (58.6 μg/ml)."

35579204

➶

reach

"Lamotrigine blocks hERG potassium channels to a significant extent in vitro, but topiramate and gabapentin have considerably less effect [27]."

29372020

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Lamotrigine inhibits KCNH2. 2 / 3

INDRA sources:

Databases

Reading