IndraLab

Statements

RELA activates USP15. 3 / 3
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"Conversely, NF-kappaBp65 also enhanced the promoter activity of USP15 and its protein expression."
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"USP15 enhances NF-κB p65 activation in a TNFα-induced, IκB-α-dependent or independent manner, while NF-κB p65, in turn, upregulates USP15 promoter activity and protein expression [48]."
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"Whereas PDTC treatment significantly decreased the luciferase Firefly and Renilla ratio, LPS treatment significantly increased that ratio when compared to untreated cells, suggesting that NF-kappaBp65 enhances the promoter activity of USP15."
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