IndraLab

Statements

UCHL1 inhibits EGFR. 2 / 2

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"As our preceding data showed that UCHL1 interacted with and stabilized EGFR (XREF_FIG to XREF_FIG), we next tested whether UCHL1 promotes cardiac hypertrophy by selectively targeting EGFR and the downstream signaling pathway."

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"Knockdown of UCHL1 significantly decreased the half-life of EGFR protein compared with the control group (XREF_FIG), whereas its half-life was markedly increased in Ad-UCHL1-infected NRCMs compared with the Ad-GFP control (XREF_FIG)."

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IndraLab

Statements

UCHL1 inhibits EGFR. 2 / 2

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