IndraLab

Statements


SMAD7 activates USP11. 2 / 2
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"We therefore hypothesized that USP11 directed by SMAD7 plays a role in balancing receptor ubiquitylation."

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"Two, we hypothesized that SMAD7 could direct USP11 DUB activity to other pathway proteins it interacts with, such as the type I TGFbeta receptors, thereby enhancing pathway signalling."