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USP18 activates immune response. 3 / 3

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"Bioinformatic analysis revealed that USP18 was positively correlated to immune infiltration of activated dendritic cells (aDCs) which implied that USP18 might be involved in DC-modulating immune response [37]."

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"Moreover, USP18 controlled exogenous IFN-gamma producing antigen specific CTL persistence in antitumor immunity."

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"Moreover, USP18 interacts with TRIM31 to promote the K63-linked polyubiquitination of MAVS and then positively regulates innate antiviral immunity (58)."

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IndraLab

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USP18 activates immune response. 3 / 3

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