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CEBPA activates USP2. 2 / 2

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"C/EBPα is a potent transcriptional factor of 11β-HSD1 in the liver, and activation of the USP2/ C/EBPα/ 11β-HSD1 signaling may account for fructose effects on MASLD (Fig. 6A)."

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"We detected the potential downstream molecules of USP2 in primary hepatocytes treated with fructose, the expression of C/EBPα (C/ebpα) and 11β-HSD1 (Hsd11b1) was significantly increased both at mRNA (Fig. 6B&C) and protein level (Fig. 6D)."

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CEBPA activates USP2. 2 / 2

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