IndraLab

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USP35 deubiquitinates SNAI1. 5 / 5
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"Altogether, we found that USP35 can deubiquitinate Snail1 and increase its expression, thereby contributing to the malignant progression of GC."
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"USP35 promoted GC cell metastasis by deubiquitinating and stabilizing Snail1."
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"Subsequently, we determined whether USP35 deubiquitinates Snail1."
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"The results shown in Fig. 3A indicate that the ectopic expression of USP35 decreased the polyubiquitination of Snail1."
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"USP35 interacts with and deubiquitinates Snail1, thereby increasing Snail1 protein levels."
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