IndraLab

Statements

CYLD activates TGFB. 3 / 3
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"Negative regulation of TGF-β signaling by CYLD was also observed in a lung fibrosis mouse model."
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"The study performed in CYLD-knockout mice reported that CYLD targets SMAD7 protein for deubiquitylation and inhibits TGF-beta signalling in the development of regulatory T cells."
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"In OSCC, down-regulation of CYLD expression significantly enhanced tumor cell invasion through epithelial-mesenchymal transition (EMT)-like changes through promoted transforming growth factor-β (TGF-β) signaling."
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