IndraLab

Statements

USP22 activates MMP9. 4 / 4
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reach
"USP22 and STAT3 co-depletion partly rescued the MMP9 proteolytic activity and invasion of SW480 cells, compared with that of STAT3 depletion alone."
25902005
reach
"In conclusion, USP22 attenuated the invasion capacity of colon cancer cells by inhibiting the STAT3 and MMP9 signaling pathway."
25902005
reach
"Other inflammatory mediators secreted by PDA cells include granulocyte colony-stimulating factor (G-CSF) (41), IL-6 (42), IL-1α (43), IL-1β (44, 45), ubiquitin specific peptidase 22 (USP22) (46), C-X-C motif chemokine ligand 8 (CXCL8) (47), matrix metallopeptidase 9 (MMP-9) and indoleamine-2,3-dioxygenase (IDO) (48), which all contribute to the establishment of immunosuppressive TME in pancreatic cancer ( Figure 1 )."
34290984
reach
"In colon cancer, USP22 was reported to attenuate the invasion capacity of colon cancer cells by inhibiting the STAT3 and MMP9 signaling pathway."
28279784