IndraLab

Statements

COPS5 activates JNK. 3 / 4
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"NRBP1 regulates the apoptotic pathway by inhibiting Jab1-mediated JNK signaling, which is essential in gene translation and regulation of cellular apoptosis (70–72); it may thus play a key role in suppressing CRC tumorigenesis."
34692549
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"MIF inhibits JAB1 and CSN5 mediated AP-1 activity and reduces JNK activity stimulated by JAB1 and CSN5."
11932196
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"In addition, MIF interaction with Jab-1 leads to the inhibition of JNK signaling pathways, which are otherwise activated by unbound Jab-1."
31414920