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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OTUD3 binds chains. 1 / 1

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"Kinetic studies using di‐Ub substrate probes (di‐Ub‐AMC) suggested that the selectivity of OTUD2 for longer K11‐linked chains is driven by affinity (lower KM), while for OTUD3, it appears to be driven by vmax, hinting that binding of K11 chains to OTUD3 may optimally reorganize the active site for catalysis."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...