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USP15 deubiquitinates RIPK1. 2 / 2

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"For example, deubiquitinase USP15 interacts with and deubiquitinates kinase RIPK1, leading to its stabilization and activation of downstream signaling pathways [47]."

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"For example, TNFAIP3, CYLD, USP3, USP4, USP15, USP25, and OTUD5 deubiquitinate key components of the IFN production pathway, including RIG-I, TRAF2, TRAF3, TRAF6, RIP1, and TRIF (reviewed in [93,94])."

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USP15 deubiquitinates RIPK1. 2 / 2

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