IndraLab

Statements



reach
"Because ZIKV uses autophagy pathway to promote viral replication and transmission during pregnancy, an autophagy inhibitor, hydroxychloroquine was shown to suppress ZIKV infection in both human tropho[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Interestingly, the anti-malarial drugs chloroquine and the related hydroxychloroquine also block ZIKV infection in vivo and prevent acidification of endosomes."

reach
"Recent evidence suggests that HCQ inhibits the ZIKV infection in placental cells and limits the vertical transmission in pregnant mice by inhibiting the autophagy pathways (142)."

eidos
"HCQ can inhibit NS2B-NS3 protease of Zika Virus and significantly decrease Zika virus infection in placental cells ."