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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CDK1 activates USP1. 2 / 2

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"Thus, cyclin dependent kinase 1 (CDK1)-mediated phosphorylation of S313 during M phase was shown to prolong the stability of USP1 presumably by preventing its degradation by the anaphase promoting complex and cyclosome [XREF_BIBR]."

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"To demonstrate that CDK1 also phosphorylates the full-length USP1, individually purified USP1 was treated with CDK1 and incuabled with UAF1 at a 1:1 molar ratio at 37 degreesC for 15 minutes."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...