IndraLab

Statements

CDK1 activates USP1. 2 / 2
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"Thus, cyclin dependent kinase 1 (CDK1)-mediated phosphorylation of S313 during M phase was shown to prolong the stability of USP1 presumably by preventing its degradation by the anaphase promoting complex and cyclosome [XREF_BIBR]."
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"To demonstrate that CDK1 also phosphorylates the full-length USP1, individually purified USP1 was treated with CDK1 and incuabled with UAF1 at a 1:1 molar ratio at 37 degreesC for 15 minutes."
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