IndraLab

Statements

USP37 inhibits E3 APC/C. 2 / 2
| 2
reach
"Established PLK1-dependent degradation substrates include EMI1 and USP37, both of which antagonize the cell-cycle E3 APC/C; WEE1, which controls cyclin-dependent kinase activity; and Claspin, which promotes DNA-damage-checkpoint signaling in S phase."
39018246
reach
"Established PLK1-dependent degradation substrates include EMI1 (Hansen et al. 2004; Moshe et al. 2004) and USP37 (Burrows et al. 2012), both of which antagonize the cell cycle E3 APC/C; WEE1 (Watanabe et al. 2004), which controls cyclin dependent kinase activity; and Claspin (Peschiaroli et al. 2006; Mailand et al. 2006; Mamely et al. 2006), which promotes DNA damage checkpoint signaling in S-phase."
37873169