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USP22 deubiquitinates BMI1. 4 / 4
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"All these findings indicate USP22 as a novel deubiquitinase of BMI1 in glioma."
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"3.3 USP22 deubiquitinates BMI1 for protein stabilization."
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"USP22 interacts with and deubiquitinates BMI1 for post-translational stabilization."
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"To test whether the endogenous BMI1 is also deubiquitinated by USP22 in glioma cells, we knocked down endogenous USP22 in U251 cells pretreated with CHX and found that endogenous BMI1 also became unstable and degraded rapidly."
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