IndraLab

Statements

BAP1 binds VCP. 12 / 12
2 | 1 9
sparser
"To further confirm the protein–protein interaction of BAP1 with VCP, we conducted co‐immunoprecipitation analysis by co‐transfecting 293T cells with plasmids encoding Flag‐tagged VCP and Myc‐tagged BAP1."
40122668
sparser
"Mechanically, VCP binds to BAP1 and promotes the latter's ubiquitination degradation via the ubiquitin‐proteasome pathway, thus promoting CCA progression."
40122668
biogrid
No evidence text available
34591877
sparser
"It identifies VCP as a key upstream regulator mediating BAP1 homeostasis: VCP binds to BAP1 and promotes the latter's ubiquitination degradation via the ubiquitin‐proteasome pathway."
40122668
sparser
"In summary, these data illustrated a physical interaction between BAP1 and VCP, suggesting that VCP may act as a novel regulator of BAP1 in CCA."
40122668
sparser
"Mechanistically, VCP binds to BAP1 and promotes the latter's ubiquitination degradation via the ubiquitin‐proteasome pathway, thus promoting cell proliferation and inhibiting cell apoptosis."
40122668
biogrid
No evidence text available
35446349
sparser
"The results showed that exogenous VCP physically interacted with BAP1 (Figure  xref )."
40122668
sparser
"We also observed interactions between Flag‐tagged VCP and endogenous BAP1 (Figure  xref ), as well as Myc‐tagged BAP1 and endogenous VCP (Figure  xref )."
40122668
reach
"Mechanistically, VCP binds to BAP1 and promotes the latter's ubiquitination degradation via the ubiquitin-proteasome pathway, thus promoting cell proliferation and inhibiting cell apoptosis."
40122668
sparser
"Similarly, as shown in Figure  xref , VCP can physically interact with BAP1 in CCA cells."
40122668
sparser
"Mechanically, VCP binds to BAP1 and induces the latter's ubiquitin‐proteasomal degradation, ultimately promoting CCA cell proliferation and inhibiting cell apoptosis."
40122668