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USP8 increases the amount of PTEN. 2 / 2

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"Our data demonstrated that ectopic expression of Flag-USP8 restored PTEN levels in UROtsa(SNHG1) cells, while USP8 knockdown attenuated PTEN levels in U5637(shSNHG1#1) cells (Fig. 5C and D)."

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"Our gain-and-loss functional assays further showed that USP8 positively regulates PTEN protein levels."

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IndraLab

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USP8 increases the amount of PTEN. 2 / 2

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