IndraLab

Statements

Glucose inhibits JUN. 5 / 6
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"Loss and gain of DKK1 function modulated HG mediated c-Jun, TGF-beta1, and fibronectin expression."
20019166
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"Adiponectin suppresses the HG induced BeWo cell proliferation by inhibiting the activation of JNK and c-jun."
25031708
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"Furthermore, addition of adiponectin to high glucose treated cells inhibited c-Jun activation, suppressing cell proliferation [45]."
30340501
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"To test whether adiponectin actually inhibits c-Jun in GDM placentas, the choriocarcinoma cell line, BeWo, was treated with high levels of glucose."
30340501
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"These results support our hypothesis that high glucose inhibits the c-Jun pathway and that IGFBP-3 can restore activity in the pathway to near normal levels."
25086184