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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

YOD1 inhibits IL1R1. 1 / 1

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"While DOX treatment alone did not significantly alter expression of these genes in HeLa parental cells (XREF_FIG), expression of YOD1 WT or C160S caused a significant decline in NF-kappaB target gene induction after IL-1beta stimulation, indicating that YOD1 can antagonize IL-1R triggered NF-kappaB signaling independent of its catalytic activity."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...