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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

SIRT1 activates ATXN3. 3 / 3

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"Altogether, these results demonstrate that SIRT1 mediates the robust neuroprotective effects of CR in MJD."

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"We then investigated whether lentiviral overexpression of SIRT1 would be sufficient to mimic the effects of CR and mediate similar alleviation of MJD pathology."

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"These results suggest that in fact SIRT1 activates autophagy in MJD mice (XREF_FIG)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

SIRT1 activates ATXN3. 3 / 3

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