IndraLab

Statements


| 3

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"Dexamethasone, a synthetic glucocorticoid that inhibits activator protein-1 (AP-1), blocked palytoxin stimulated MMP-13 gene expression."

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"Dexamethasone suppressed the abundance of the c, Fos/c, and Jun complex in THP-1 cell nuclei, but there was no direct evidence for c-Fos and c-Jun transactivation through sites in the -172 to -52 bp region."

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"Dexamethasone (DEX), a synthetic GC, was reported to inhibit the inflammatory response by downregulating the transcription factor AP-1 in human lung epithelial cells [XREF_BIBR]."
| PMC