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USP18 activates STING1. 2 / 4

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"In addition, USP18 can recruit the deubiquitinase USP20 to deconjugate the ubiquitination of STING and enhance the stability of STING and the induction of IFN-I and inflammatory cytokines during DNA virus infection [96]."

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"And, Zhang M. et al. have reported that USP18 recruits USP20 to deconjugate K48 linked ubiquitination chains from STING and promotes the stability of STING [XREF_BIBR]."

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USP18 activates STING1. 2 / 4

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