IndraLab

Statements

TLR4 binds IL10. 8 / 8
| 2 6
reach
"In conclusion we found an association between IL10, FAS, and TLR4 in the donor and IL18 in the recipient and an increased risk of developing aGvHD in transplanted children."
25973432
sparser
"Intestinal microbiota composition before peroral association of TLR4 deficient IL10 −/− mice with multi-drug resistant P. aeruginosa ."
29151895
sparser
"xref indicates the sequence of 3'UTR where IL-10 and TLR4 mRNA bound to rno-miR-30b-5p."
30510488
sparser
"Intestinal colonization properties of multi-drug resistant P. aeruginosa following peroral association of TLR4 deficient IL10 −/− mice."
29151895
reach
"The key and novel findings include : 1) Both hepatocyte and myeloid cell TLR4 is required for maximal I/R associated injury; 2) DC TLR4 -/- worsens injury after I/R and is associated with decreased IL-10 expression; 3) Hepatocytes are a major source of circulating HGMB1 after I/R; 4) Hepatocytes respond to hypoxia with increased phosphorylation of MAP kinases, JNK and p38, in a TLR4 dependent fashion; 5) Hypoxia induced HMGB1 release from hepatocytes is dependent on the function of JNK."
23460269
sparser
"This way, TLR9 and IL-10 exhibit double genetic interaction with each other, TLR9 interacts with IL-6 and IL-8, and IL-10 interacts with TLR4."
30116270
sparser
"Hence, TLR4 deficiency of PA-colonized IL10 –/– mice is associated with less distinct innate as well as adaptive immune cell responses in the large intestines."
29034110
sparser
"Decreased LPS-induced IL-12(p70) and IL-10 responses were associated with the TLR4 (Asp299Gly) polymorphism and independently with asthma, especially atopic asthma."
15356557