IndraLab

Statements


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sparser
"xref indicates the sequence of 3'UTR where IL-10 and TLR4 mRNA bound to rno-miR-30b-5p."

sparser
"The clustering of regulatory T (Treg) cells in hepatoma cell lines could be indirectly promoted by the interaction of TLR4 with macrophages, accompanied by the upregulation of IL-10 and C-C class chemokine 22 (CCL22) expression ( xref )."

reach
"By constructing a network of protein-protein interactions (PPIs), we identified six key proteins (TNF, IL6, TLR4, IL1β, IL10, and IL8) that exhibited substantial interactions (more than 30 edges), suggesting their potential as significant targets for influencing malaria susceptibility."

sparser
"This way, TLR9 and IL-10 exhibit double genetic interaction with each other, TLR9 interacts with IL-6 and IL-8, and IL-10 interacts with TLR4."

reach
"The key and novel findings include : 1) Both hepatocyte and myeloid cell TLR4 is required for maximal I/R associated injury; 2) DC TLR4 -/- worsens injury after I/R and is associated with decreased IL-10 expression; 3) Hepatocytes are a major source of circulating HGMB1 after I/R; 4) Hepatocytes respond to hypoxia with increased phosphorylation of MAP kinases, JNK and p38, in a TLR4 dependent fashion; 5) Hypoxia induced HMGB1 release from hepatocytes is dependent on the function of JNK."

sparser
"Intestinal colonization properties of multi-drug resistant P. aeruginosa following peroral association of TLR4 deficient IL10 −/− mice."

sparser
"Present study also shows that there is IL-10 and TLR4 interaction in the cellular innate signaling upon specific ligand stimulation."

sparser
"Hence, TLR4 deficiency of PA-colonized IL10 –/– mice is associated with less distinct innate as well as adaptive immune cell responses in the large intestines."

sparser
"Intestinal microbiota composition before peroral association of TLR4 deficient IL10 −/− mice with multi-drug resistant P. aeruginosa ."

reach
"In conclusion we found an association between IL10, FAS, and TLR4 in the donor and IL18 in the recipient and an increased risk of developing aGvHD in transplanted children."

sparser
"Whether IL-10 activates TLR4 via activation of IL-10R on cardiomyocytes, a competitive inhibition study using 10 μg/ml of clone 1B1.3a, an IL-10R antibody [31] was also carried out to understand the m[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Present study also shows that there is IL-10 and TLR4 interaction in the cellular innate signaling upon specific ligand stimulation."