IndraLab

Statements

reach
"Especially STAMBPL1 could modulate the stability of TRAF2 protein and activate WNT/PI3K/NF-kb signalling pathway."
38419066
reach
"Our study reveals for the first time that GRHL3 promotes transcriptional activity by binding to the promoter of the HIF1A gene.In this study, we utilized two TNBC cell lines, HCC1806 and HCC1937, along with human primary umbilical vein endothelial cells (HUVECs) and a nude mouse breast orthotopic transplantation tumor model to investigate the regulatory mechanism by which STAMBPL1 activates the GRHL3/HIF1α/VEGFA signaling pathway through its interaction with FOXO1, thereby promoting angiogenesis in TNBC."
40208233